免疫学
类风湿性关节炎
生物
自身抗体
免疫系统
发病机制
自身免疫
自身免疫性疾病
抗体
作者
Ru Li,Xiaohuan Sun,Xu Liu,Yue Yang,Zhanguo Li
出处
期刊:Advances in Immunology
日期:2019-01-01
卷期号:: 173-216
被引量:12
标识
DOI:10.1016/bs.ai.2019.09.002
摘要
Autoimmune diseases, such as rheumatoid arthritis, systematic lupus erythematosus and Sjögren's syndrome, are a group of diseases characterized by the activation of immune cells and excessive production of autoantibodies. Although the pathogenesis of these diseases is still not completely understood, studies have shown that multiple factors including genetics, environment and immune responses play important roles in the development and progression of the diseases. In China, there are great achievements in the mechanisms of autoimmune diseases during the last decades. These studies provide new insight to understand the diseases and also shed light on the development of novel therapy.
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