旁侵犯
医学
前列腺切除术
生化复发
病态的
组织病理学
组织病理学检查
病理
腺癌
前列腺
阶段(地层学)
泌尿科
癌症
内科学
生物
古生物学
作者
Yelda Dere,Aysegu Aksoy Altinboga,Kaan Bal,Aylin Örgen Çallı,Murat Ermete,Ayşegül Sarı
出处
期刊:PubMed
日期:2017-04-01
卷期号:27 (4): 213-217
被引量:3
摘要
To determine the relationship between biochemical recurrence and other histopathological factors in prostate cancer.Analytical study.Pathology and Urology Departments, Izmir Ataturk Training and Research Hospital, between 2001 - 2013.117 cases diagnosed with prostatic adenocarcinoma and treated by radical prostatectomy were reviewed retrospectively for histopathological features; whereas, other prognostic findings were noted. PSA levels and many other histopathological parameters were assessed in order to put forth their effect on biochemical recurrence.PSA level (p<0.001), tumor volume (p<0.001), Gleason score (p<0.001), extraprostatic extension (p<0.001), perineural invasion (p<0.001), ganglion involvement (p=0.040), vascular invasion (p<0.001), positive surgical margins (p<0.001), presence of tertiary pattern (p=0.004) and the involvement of the seminal vesicles (p<0.001) were found to be statistically related to the pathological stage. Age, perineural invasion, high grade tertiary pattern, intraluminal mucin, collagenous micronodules and foamy cytoplasmic changes were unrelated to recurrence.Histopathological features can be helpful in predicting prognosis in prostatic adenocarcinomas. However some of the histopathological factors such as intraluminal mucin and foamy cytoplasmic changes may not reflect high recurrence.
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