Biomimetic polysaccharide-cloaked lipidic nanovesicles/microassemblies for improving the enzymatic activity and prolonging the action time for hyperuricemia treatment

We prepare biomimetic polysaccharide hyaluronan-cloaked lipidic nanovesicles/microassemblies by entrapping uricase in the core of the hollow vesicles or by tethering them to the surfaces and then perform an antihyperuricemia evaluation of them.