医学
心脏再同步化治疗
心室
射血分数
心脏病学
内科学
QRS波群
左束支阻滞
心力衰竭
人口
右束支阻滞
心脏病
心电图
环境卫生
作者
Yakup Ergül,Fatma Sevinç Şengül,Erkut Öztürk,Hasan Kafalı,Pelin Ayyıldız,İbrahim Cansaran Tanıdır,Halil Sencer Akdeniz,Mustafa Güneş,Okan Yıldız,Sertaç Haydın,Alper Güzeltaş
出处
期刊:Cardiology in The Young
[Cambridge University Press]
日期:2021-01-27
卷期号:31 (6): 940-948
被引量:3
标识
DOI:10.1017/s1047951120004795
摘要
Abstract Objectives: In recent years, cardiac resynchronization therapy (CRT) has also started to be performed in the paediatric and CHD population. This study aimed to evaluate the efficacy of CRT in children with CHD. Patients and methods: Patients with CHD who underwent CRT treatment in our paediatric cardiology clinic between January, 2010 and January, 2020 were included in the study. Demographic findings, 12-lead electrocardiograms, echocardiograms, clinical characteristics, management strategies, and outcomes were reviewed systematically. Results: The study population consisted of 18 CHD patients who had been treated with CRT for 10 years in our institution. The median age was 11 years (2.2–18 years) and the median weight was 39 kg (10–81 kg). Systemic ventricle was left ventricle in 13 patients, right ventricle in 4 patients, and 1 patient had single-ventricle physiology. CRT implantation indications were as follows: dysfunction after permanent pacemaker in 11 patients, dysfunction after left bundle branch block in 4 patients, and systemic ventricular dysfunction in 3 patients. CRT implantation techniques were epicardial (n = 13), hybrid (n = 4), and transvenous (n = 1) methods. QRS duration significantly decreased after CRT implantation (160 versus 124 m/second, p < 0.05). Median systemic ventricle ejection fraction (EF) significantly increased after the procedure (30 versus 50%, p < 0.05). Fourteen patients (78%) were responders, two patients (11%) were superresponders, and two patients (11%) were non-responders after the CRT treatment. One patient deceased during follow-up. Median follow-up duration was 40 months (6–117 months). Conclusion: When electromechanical dyssynchrony occurs in paediatric cases with CHD and developing heart failure, patients should be evaluated in terms of CRT to improve ventricular function. Alternative CRT therapy will be beneficial in these cases that do not improve clinically despite optimal medical treatment.
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