Comparison of antibiotic-resistant bacteria and antibiotic resistance genes abundance in hospital and community wastewater: A systematic review

抗生素 抗生素耐药性 抗药性 废水 环境卫生 微生物学 医学 生物 环境科学 环境工程
作者
Nasreen Hassoun‐Kheir,Yoav Stabholz,Jan‐Ulrich Kreft,Roberto de la Cruz,Jesús L. Romalde,Joseph Nesme,Søren J. Sørensen,Barth F. Smets,David W. Graham,Mical Paul
出处
期刊:Science of The Total Environment [Elsevier BV]
卷期号:743: 140804-140804 被引量:169
标识
DOI:10.1016/j.scitotenv.2020.140804
摘要

Antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) are constantly shed into the aquatic environment, with hospital wastewater potentially acting as an important source for resistance spread into the environment. A systematic review was conducted aiming to investigate the role of hospital wastewater on dissemination of antimicrobial resistance in the aquatic environment. Studies included in the review compared the prevalence of ARB and/or ARGs in hospital versus community wastewater. Data were extracted on ARB and/or ARG prevalence. Data on sampling techniques, microbiological methodology and risk of bias of included studies were recorded. Thirty-seven studies were included. Higher frequencies of antibiotic resistance determinants were found in hospital wastewater compared to community sources in 30/37 (81%) of included studies. However, trends for specific multi-drug-resistant bacteria differed. Antibiotic-resistant Gram-negative were more prevalent in hospital compared to community wastewaters, with higher concentrations of extended-spectrum-beta-lactamase-producing pathogens and carbapenemase-producing Enterobacteriaceae in hospital sources in 9/9 studies and 6/7 studies, respectively. Hospitals did not contribute consistently to the abundance of vancomycin-resistant Enterococci (VRE); 5/10 studies found higher abundance of VRE in hospital compared to community wastewaters. Reporting on sampling methods, wastewater treatment processes and statistical analysis were at high risk of bias. Extreme heterogeneity in study methods and outcome reporting precluded meta-analysis. Current evidence concurs that hospital wastewater is an important source for antibiotic resistance in aquatic environments, mainly multidrug-resistant Gram-negative bacteria. Future research is needed to assess the effect of wastewater treatment processes on overall antibiotic resistance in the aquatic environment.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
2秒前
4秒前
笨笨青筠完成签到 ,获得积分10
7秒前
mengmenglv完成签到 ,获得积分0
7秒前
Tonald Yang完成签到 ,获得积分20
10秒前
11秒前
落后的怀梦完成签到 ,获得积分10
12秒前
陈坤完成签到,获得积分10
14秒前
量子星尘发布了新的文献求助10
16秒前
斯文败类应助zgx采纳,获得10
17秒前
默默完成签到 ,获得积分10
17秒前
KY Mr.WANG完成签到,获得积分10
17秒前
31秒前
guoxingliu完成签到,获得积分10
35秒前
43秒前
阳佟水蓉完成签到,获得积分10
44秒前
gdgd完成签到,获得积分10
47秒前
量子星尘发布了新的文献求助10
49秒前
叮叮当当完成签到,获得积分10
51秒前
54秒前
54秒前
电致阿光完成签到,获得积分10
55秒前
ccc完成签到 ,获得积分10
57秒前
58秒前
zgx发布了新的文献求助10
1分钟前
i2stay完成签到,获得积分10
1分钟前
馒头完成签到,获得积分10
1分钟前
MS903完成签到,获得积分10
1分钟前
CJW完成签到 ,获得积分10
1分钟前
韧迹完成签到 ,获得积分0
1分钟前
mmd完成签到 ,获得积分10
1分钟前
七一安完成签到 ,获得积分10
1分钟前
浪麻麻完成签到 ,获得积分10
1分钟前
包容的剑完成签到 ,获得积分10
1分钟前
等待的大炮完成签到,获得积分10
1分钟前
注水萝卜完成签到 ,获得积分10
1分钟前
Chem34完成签到,获得积分10
1分钟前
1分钟前
量子星尘发布了新的文献求助10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038039
求助须知:如何正确求助?哪些是违规求助? 3575756
关于积分的说明 11373782
捐赠科研通 3305574
什么是DOI,文献DOI怎么找? 1819239
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022