已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

P217 Clinical efficacy of complex phytopreparation based on evening primrose, gentian, elder, sorrel, verbena as a therapeutic agent in treatment of acute viral rhinosinusitis in children

医学 傍晚 内科学 天文 物理
作者
Galyna Beketova,Vasyl I. Popovich,Oleksandr Abaturov,Т.O. Kryuchko,Olga Tsodikova,Lyudmyla Vakulenko
出处
期刊:Abstracts 卷期号:: A244.1-A244
标识
DOI:10.1136/archdischild-2019-epa.569
摘要

Trial objective/hypothesis

Investigation of the benefits of treatment of acute viral RS with complex phytopreparation as a basic therapeutic agent in contrast to routine therapy based on the symptomatic treatment.

Products

Complex phytopreparation syrup BNO 1012

Trial design

Clinical, Non-interventional, Multicentre (5 clinical centres in four cities), Prospective, Randomized, Comparative

Subjects

Patients diagnosed with acute viral RS (n=169): Age: 6–11, average age 8.1; Sex: male (n=88)/female (n=81); The main group (n=94); The comparison group (n=76)

Inclusion criteria

Acute viral RS; First 48 hours since onset of the disease; Severity of symptoms – 8 to 12 points on the MSS scale: nasal discharge, nasal congestion, post-nasal drip, headache, facial pain (0–4 points).

Exclusion criteria

Administration of complex phytopreparation for 30 days prior to the episode; Patients diagnosed with allergic rhinosinusitis; Known intolerance to primrose drugs; More than 48 hours since onset of the disease; Severe acute disease requiring hospitalization/treatment with antibiotics; Chronic pathology and anatomical anomalies in osteomeatal complex, which may influence outcome of the disease. Primary/Secondary efficacy criteria Decrement of RS symptoms on the MSS scale; Recovery day / Reduction in frequency of transition to post-viral RS stage; Reduction in frequency of transition to purulent RS stage

Duration of treatment

14 days.

Physical examination

Visit 1 (day 0); Visit 2 (day 5); Visit 3 (day 10); Visit 4 (day 14) Patient's self-evaluation daily for 10 days.

Conclusions

Administration of complex preparation for treatment of acute viral RS among children at the age of 6–11 leads to: Substantial decrement of RS symptoms on the MSS scale starting with visit 2; There was no statistical difference between groups in terms of dynamics of 'facial pain' and 'headache' criteria, due to the toxic effects of the viral infection; Reduction of duration of disease by almost 24 hours; Substantial reduction in frequency of transition of acute viral RS to post-viral RS stage (by 79.5%) and bacterial RS stage (by 58.7%).
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
小秦秦完成签到 ,获得积分10
1秒前
orixero应助Lulu采纳,获得10
1秒前
哲别发布了新的文献求助10
2秒前
高大的友梅完成签到 ,获得积分10
2秒前
zzzxxxxxyyyyy发布了新的文献求助10
3秒前
doocan完成签到,获得积分10
3秒前
ppg123应助西瓜二郎采纳,获得10
3秒前
momo发布了新的文献求助10
3秒前
隐形曼青应助漂亮白枫采纳,获得10
4秒前
务实觅松完成签到 ,获得积分10
5秒前
coolkid应助负责怀莲采纳,获得10
5秒前
6秒前
YYYZZX1发布了新的文献求助10
6秒前
自由的聋五完成签到,获得积分10
6秒前
木槿花难开完成签到,获得积分10
6秒前
Del完成签到,获得积分10
10秒前
CNX发布了新的文献求助10
11秒前
范范778完成签到 ,获得积分10
11秒前
852应助YYYZZX1采纳,获得10
11秒前
11秒前
不羁完成签到 ,获得积分10
11秒前
12秒前
科研通AI2S应助希特勒采纳,获得10
13秒前
Del发布了新的文献求助10
14秒前
笑笑完成签到 ,获得积分10
14秒前
飞快的老太完成签到,获得积分10
15秒前
16秒前
Hello应助哲别采纳,获得10
16秒前
17秒前
17秒前
打打应助xxxrass采纳,获得10
19秒前
Linyi完成签到,获得积分10
19秒前
冰棒比冰冰完成签到 ,获得积分10
19秒前
西瓜二郎完成签到,获得积分10
21秒前
科研通AI2S应助congenialboy采纳,获得10
23秒前
zsc668发布了新的文献求助10
23秒前
25秒前
dehai li发布了新的文献求助10
25秒前
jiusi完成签到 ,获得积分10
27秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989832
求助须知:如何正确求助?哪些是违规求助? 3531967
关于积分的说明 11255613
捐赠科研通 3270725
什么是DOI,文献DOI怎么找? 1805035
邀请新用户注册赠送积分活动 882181
科研通“疑难数据库(出版商)”最低求助积分说明 809208