癫痫
尸检
医学
病因学
皮质发育不良
死因
儿科
法医病理学
猝死
发育不良
脑裂
病理
作者
Richard D. Jordan,Matthew Coscia,Patrick Lantz,William Harrison
出处
期刊:American Journal of Forensic Medicine and Pathology
[Ovid Technologies (Wolters Kluwer)]
日期:2022-05-30
卷期号:43 (3): 259-262
标识
DOI:10.1097/paf.0000000000000773
摘要
Sudden unexplained death in epilepsy (SUDEP) is the most common cause of death in children and young adults with epilepsy with epileptic patients harboring a 27 times increased risk of death from SUDEP. Structural brain lesions are encountered in up to 50% of autopsy cases. In this case series, we report 3 previously undiagnosed structural causes of SUDEP discovered at autopsy at our institution including schizencephaly, ganglioglioma, and focal cortical dysplasia. Our major recommendation is in cases with suspected SUDEP, formal neuropathological examination and tissue sampling should be employed to identify and characterize specific potential anatomic etiologies.
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