谵妄
脑电图
右美托咪定
神经认知
重症监护室
医学
睡眠(系统调用)
发作性
睡眠纺锤
病危
快速眼动睡眠
睡眠架构
眼球运动
多导睡眠图
重症监护医学
神经科学
慢波睡眠
镇静
麻醉
心理学
认知
精神科
计算机科学
操作系统
作者
Madeleine Grigg‐Damberger,Omar Hussein,Tobias Kulik
出处
期刊:Journal of Clinical Neurophysiology
[Ovid Technologies (Wolters Kluwer)]
日期:2022-01-17
卷期号:39 (5): 372-382
被引量:8
标识
DOI:10.1097/wnp.0000000000000830
摘要
Summary: In this narrative review, we summarize recent research on the prognostic significance of biomarkers of sleep in continuous EEG and polysomnographic recordings in intensive care unit patients. Recent studies show the EEG biosignatures of non-rapid eye movement 2 sleep (sleep spindles and K-complexes) on continuous EEG in critically ill patients better predict functional outcomes and mortality than the ictal–interictal continuum patterns. Emergence of more complex and better organized sleep architecture has been shown to parallel neurocognitive recovery and correlate with functional outcomes in traumatic brain injury and strokes. Particularly interesting are studies which suggest intravenous dexmedetomidine may induce a more biomimetic non-rapid eye movement sleep state than intravenous propofol, potentially providing more restorative sleep and lessening delirium. Protocols to improve intensive care unit sleep and neurophysiological studies evaluating the effect of these on sleep and sleep architecture are here reviewed.
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