亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Persistent Shoulder Pain After Vaccine Administration Is Associated with Common Incidental Pathology: A Systematic Review

医学 荚膜炎 滑囊炎 肩袖 接种疫苗 肩袖损伤 肌腱病 物理疗法 梅德林 外科 病理 肌腱 运动范围 政治学 法学
作者
Erik L. Slette,Mitchell Rohrback,David Ring
出处
期刊:Clinical Orthopaedics and Related Research [Lippincott Williams & Wilkins]
卷期号:480 (7): 1251-1258 被引量:2
标识
DOI:10.1097/corr.0000000000002191
摘要

Claims of shoulder injury now account for half of all claims to the Vaccine Injury Compensation Program. Reports from databases of claims or potential adverse events note a relatively high mean age and high prevalences of rotator cuff tendinopathy and adhesive capsulitis-common shoulder problems that might be incidental to vaccination. Published case reports provide much more detail about individual patients than is available in databases. A review of published cases provides an opportunity for more detailed review of symptoms, diagnoses, pathology, treatment, and prognosis. Such a review can better assess the relative likelihood that pathologies associated with new persistent shoulder symptoms after vaccination are coincidental or unique to and caused by vaccine.Regarding published case reports addressing persistent shoulder pain after vaccination: (1) In what proportion of patients was a specific diagnosis made? (2) What diagnoses were most common? (3) Among patients treated nonsurgically, what proportion resolved, and over what time span did they resolve?In August 2020, we searched PubMed and Embase between 2006 and 2020 using the following search strategy: Search 1: (shoulder dysfunction OR shoulder pain OR shoulder bursitis OR rotator cuff tendonitis OR adhesive capsulitis OR glenohumeral arthritis AND [vaccine OR vaccination OR immunization]); Search 2: (shoulder injury related to vaccine administration or SIRVA). The search was supplemented by reviewing reference lists of identified studies. Inclusion criteria were any detailed report of three or fewer cases involving shoulder pain after vaccine administration. Twenty published reports of 29 patients were identified and assessed by two reviewers independently. One reported glenohumeral joint infection was excluded because the relationship between this type of relatively uncommon, discrete diagnosis and vaccination raises different considerations. We assumed a high risk of bias, although we are not aware of bias assessment tool for case reports. We recorded and summarized patient demographics, symptoms, examination and imaging findings, surgery findings, diagnoses, treatments, and outcomes. Seventy-five percent (21 of 28) of patients were women, with a mean age of 54 ± 19 years. In search of an underlying pathology, at least one diagnostic study was performed in 82% (23 of 28) of patients including radiographs in seven, ultrasound in seven, and MRI in 16 patients (some patients underwent more than one type of imaging). We distinguished specific pathophysiological diagnosis from shoulder pain and stiffness, counted the most common diagnoses among patients a specific diagnosis, and tracked symptom resolution among patients treated nonoperatively.A specific diagnosis was made in 57% (16 of 28) of patients. Twelve patients had pain and limitation of motion due to pain but no specific pathological diagnosis. The most common specific diagnoses were rotator cuff tendinopathy (9 of 16) and adhesive capsulitis (4 of 16). Less common specific diagnoses included rotator cuff arthropathy (and rheumatoid arthritis) and suspected septic arthritis with nonspecific synovitis on arthroscopy. One patient had transient MRI signal change in the humeral head, which was interpreted as osteonecrosis that resolved in a manner not typical for that diagnosis. Of the 17 patients treated nonsurgically, 15 reported resolution, and two had incomplete symptom resolution with the mean 6-month evaluation period.The observation that persistent shoulder pain after vaccination overlaps with common shoulder pathology-both in large databases as well as in more detailed reports of specific patients as analyzed in this review-establishes a high probability of a coincidental rather than a causal association. In the absence of high-quality experimental evidence of vaccine-specific shoulder pathology, in our opinion, it seems safest and healthiest to assume that perceived shoulder injury related to vaccine administration (SIRVA) is due to misinterpretation of new symptoms from established pathology rather than a new, vaccine-specific pathology.Level IV, therapeutic study.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
量子星尘发布了新的文献求助10
17秒前
30秒前
葛力发布了新的文献求助10
34秒前
彩色的紫丝完成签到 ,获得积分10
36秒前
fangyifang完成签到,获得积分10
42秒前
xxx完成签到,获得积分20
45秒前
49秒前
49秒前
xxx发布了新的文献求助20
50秒前
Tethys完成签到 ,获得积分10
50秒前
55秒前
Akim应助大方研究生采纳,获得10
1分钟前
1分钟前
孙雁哝发布了新的文献求助10
1分钟前
yx_cheng应助科研通管家采纳,获得10
1分钟前
深情安青应助科研通管家采纳,获得10
1分钟前
Orange应助qyn1234566采纳,获得10
1分钟前
小飞飞发布了新的文献求助10
1分钟前
1分钟前
羊白玉完成签到 ,获得积分10
1分钟前
充电宝应助wyx采纳,获得10
1分钟前
万能图书馆应助小飞飞采纳,获得10
1分钟前
暖暖完成签到,获得积分10
1分钟前
孙雁哝完成签到,获得积分10
1分钟前
量子星尘发布了新的文献求助10
1分钟前
2分钟前
2分钟前
wyx发布了新的文献求助10
2分钟前
2分钟前
菲菲酱完成签到 ,获得积分10
2分钟前
RAIN发布了新的文献求助10
2分钟前
量子星尘发布了新的文献求助30
2分钟前
MLS8620应助aa采纳,获得10
2分钟前
HuiHui完成签到,获得积分10
2分钟前
李健应助RAIN采纳,获得10
2分钟前
yx_cheng应助科研通管家采纳,获得10
3分钟前
打打应助科研通管家采纳,获得10
3分钟前
SciGPT应助科研通管家采纳,获得10
3分钟前
自然芷文完成签到,获得积分10
3分钟前
雨过天晴完成签到,获得积分10
3分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Social Research Methods (4th Edition) by Maggie Walter (2019) 2390
A new approach to the extrapolation of accelerated life test data 1000
北师大毕业论文 基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 390
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 360
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4008109
求助须知:如何正确求助?哪些是违规求助? 3547893
关于积分的说明 11298611
捐赠科研通 3282850
什么是DOI,文献DOI怎么找? 1810216
邀请新用户注册赠送积分活动 885957
科研通“疑难数据库(出版商)”最低求助积分说明 811188