ABO血型系统
抗体
医学
血型(非人类)
淋巴瘤
打字
活检
B细胞
内科学
免疫学
胃肠病学
生物
遗传学
作者
Hee‐Jeong Youk,Jin Seok Kim,Hyungsuk Kim,Sang‐Hyun Hwang,Heung‐Bum Oh,Yousun Chung,Dae‐Hyun Ko
标识
DOI:10.1016/j.transci.2022.103450
摘要
ABO antibodies occur naturally and usually exist as alloantibodies. They are the most clinically significant in cases of transfusions. However, there are very few reports on auto-anti-A or B. A 58-year-old man visited our hospital for evaluation of an inguinal mass. Blood typing was performed, while preparing the patient for an excisional biopsy. Forward and reverse typing showed a typical AB and A pattern. Results of the direct antiglobulin and unexpected antibody screening tests were negative. The serum did not react with AB3 cells. The biopsy revealed a diffuse large B-cell lymphoma. After completing four cycles of R-CHOP chemotherapy, the patient achieved complete remission. There were no anti-B antibodies found on repeat ABO typing. This report shares our experience on unexpected anti-B antibody findings in a patient with an A1B blood type. To the best of our knowledge, this is the first report of anti-B antibodies in a patient with an A1B blood type in Korea.
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