医学
生物标志物
胰岛素抵抗
索引(排版)
甘油三酯
血管病学
代理终结点
疾病
糖尿病
内科学
胰岛素
内分泌学
胆固醇
计算机科学
化学
万维网
生物化学
作者
Lichan Tao,Jia-ni Xu,Tingting Wang,Fei Hua,Jian‐Jun Li
标识
DOI:10.1186/s12933-022-01511-x
摘要
Abstract The triglyceride-glucose (TyG) index has been identified as a reliable alternative biomarker of insulin resistance (IR). Recently, a considerable number of studies have provided robust statistical evidence suggesting that the TyG index is associated with the development and prognosis of cardiovascular disease (CVD). Nevertheless, the application of the TyG index as a marker of CVD has not systemically been evaluated, and even less information exists regarding the underlying mechanisms associated with CVD. To this end, in this review, we summarize the history of the use of the TyG index as a surrogate marker for IR. We aimed to highlight the application value of the TyG index for a variety of CVD types and to explore the potential limitations of using this index as a predictor for cardiovascular events to improve its application value for CVD and provide more extensive and precise supporting evidence.
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