Adjunctive treatment of bronchiectasis infection with ambroxol and sodium bicarbonate through sequential lavage:an efficacy analysis

Objective To investigate the efficacy and significance of ambroxol and sodium bicarbonate through sequential lavage in treatment of bronchiectasis infection.Method The patients were randomly divided into conventional treatment group(control group) and the other group which combined conventional therapy with adjunctive therapy of ambroxol and sodium bicarbonate through sequential lavage(observation group).The clinical efficacy ofthe two groups were analyzed after 2 weeks and the frequency of exacerbation were followed up in six months.Result The total effective rate and half year frequency of exacerbation of the observation group,compared with the control group,were significantly different(P0.05,P0.01).Conclusion The adjunctive therapy of ambroxol and sodium bicarbonate through sequential lavage based on conventional therapy can enhance the curative effectiveness,reduce the frequency of acute exacerbation,and improve the half-year quality of life in bronchiectasis infection.