Curative Effect of Victoria Medicine Qubaibabuqi Capsule on Experimental Vitiligo in Guinea Pigs

Objective To study the curative effect of victoria medicine qubaibabuqi capsule on experimental vitiligo in guinea pigs. Methods The animal model of vitiligo was prepared by decolourization process of hydroquinone production,then the model animals were treated with different doses of qubaibabuqi capsule.After the medical treatment,dopamine and iron staining were used for observing the changes of melanocytes and black granules,and immunohistochemisty was used to test the content of tyrosine. Results Compared with the model group,the count of melanocytes and basal cells with black pigment particles and the tyrosine's expression in the treatment groups were significantly higher by the end of experiment(P0.01). Conclusion The victoria medicine qubaibabuqi capsule can increase epidermal melanocytes and production of black granules and enhance the expression of tyrosine.