脑-机接口
经颅直流电刺激
脑电图
康复
物理医学与康复
心理学
运动表象
冲程(发动机)
功能性电刺激
神经影像学
神经科学
医学
刺激
机械工程
工程类
作者
Ravikiran Mane,Effie Chew,Kok Soon Phua,Kai Keng Ang,A. P. Vinod,Cuntai Guan
标识
DOI:10.1109/embc.2018.8512920
摘要
This study investigates the neurological changes in the brain activity of chronic stroke patients undergoing different types of motor rehabilitative interventions and their relationship with the clinical recovery using the Quantitative Electroencephalography (QEEG) features. Over a period of two weeks, 19 hemiplegic chronic stroke patients underwent 10 sessions of upper extremity motor rehabilitation using a brain-computer interface paradigm (BCI group, n=9) and transcranial direct current stimulation coupled BCI paradigm (tDCS group, n=10). The pre- and post-treatment brain activations, as well as the intervention-induced changes in the neuronal activity, were quantified using 11 QEEG features and their relationship with clinical motor improvement was investigated. Significant treatment-induced change in the relative theta power was observed in the BCI group and the change was significantly correlated with the clinical improvements. Also, in the BCI group, the relative theta power and interactions between the theta, alpha, and beta power were identified as monitory biomarkers of motor recovery. On the contrary, the tDCS group was characterized by the significant change in brain asymmetry. Furthermore, we observed significant intergroup differences in the predictive capabilities of post-intervention QEEG features between the BCI and tDCS group. Based on the intergroup differences observed in this study and convergent results from the other neuroimaging analysis performed on the same cohort, we suggest that distinctly different mechanisms of neuronal recovery were facilitated by tDCS and BCI interventions and these treatment specific mechanisms can be encapsulated using QEEG.
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