Altered Small-world Brain Network in Sleep Deprivation

In this study, we investigated the changes in topological architectures of brain functional networks in sleep deprivation. By collecting participants in sleep deprivation of functional magnetic resonance imaging (fMRI), our result shows that the functional brain network of the clustering coefficient, characteristic path length and local efficiency are significantly increased but the global efficiency decreased significantly in sleep deprivation. Additionally, significant alterations in nodal efficiency were also found in sleep deprivation, involving anterior cingulate, inferior parietal, supramarginal gyrus, caudate nucleus, thalamus are significant decreased, and themiddle temporal gyrus are significant increased.