免疫原性
人类蛋白质
计算生物学
重组DNA
抗体
生物
免疫学
医学
病毒学
遗传学
基因
作者
Suzanne Hermeling,Daan J.A. Crommelin,Huub Schellekens,Wim Jiskoot
出处
期刊:Pharmaceutical Sciences Encyclopedia
日期:2010-03-15
卷期号:: 1-19
被引量:1
标识
DOI:10.1002/9780470571224.pse315
摘要
Abstract The introduction of recombinant DNA techniques has made possible to produce proteins on a large scale. These protein therapeutics are potentially immunogenic, inducing antibodies in patients after a certain period of treatment. This article gives an overview of the current knowledge about the immunogenicity of therapeutic proteins.
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