作者
Chris Parker,Sten Nilsson,Daniel Heinrich,Svein Inge Helle,Joe M. O’Sullivan,Sophie D. Fosså,Aleš Chodacki,Paweł Wiechno,John Logue,M. Seke,Anders Widmark,Dag Clement Johannessen,Peter Hoskin,David Bottomley,Nicholas D. James,A. Solberg,Isabel Syndikus,J. Kliment,Saskia Wedel,S. Boehmer,Marcos F. Dall’Oglio,Lars Franzén,Robert E. Coleman,Nicholas J. Vogelzang,C. Gillies O'Bryan-Tear,K. Staudacher,J. Garcia‐Vargas,Minghua Shan,Øyvind S. Bruland,Oliver Sartor
摘要
Radium-223 dichloride (radium-223), an alpha emitter, selectively targets bone metastases with alpha particles. We assessed the efficacy and safety of radium-223 as compared with placebo, in addition to the best standard of care, in men with castration-resistant prostate cancer and bone metastases.