镭-223
医学
前列腺癌
镭
危险系数
安慰剂
中期分析
泌尿科
置信区间
临床终点
癌症
外科
内科学
核医学
随机对照试验
骨转移
病理
物理
替代医学
核物理学
作者
Chris Parker,Sten Nilsson,Daniel Heinrich,Svein Inge Helle,Joe M. O’Sullivan,Sophie D. Fosså,Aleš Chodacki,Paweł Wiechno,John Logue,M. Seke,Anders Widmark,Dag Clement Johannessen,Peter Hoskin,David Bottomley,Nicholas D. James,A. Solberg,Isabel Syndikus,J. Kliment,Saskia Wedel,S. Boehmer
标识
DOI:10.1056/nejmoa1213755
摘要
Radium-223 dichloride (radium-223), an alpha emitter, selectively targets bone metastases with alpha particles. We assessed the efficacy and safety of radium-223 as compared with placebo, in addition to the best standard of care, in men with castration-resistant prostate cancer and bone metastases.
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