Influence of Metal Cations on the Structure and Release Property of Layered Double Hydroxide-Ibuprofen Host-Guest Materials

Layered double hydroxide (LDH)-ibuprofen (IBU) host-guest materials were prepared by in situ coprecipitation method for the purpose of drug controlled release. Three hosts containing different metal cations, MgAl-, ZnAl-, and MgFe-LDH, were studied. The results showed that the types of the metal cations had great influence on the structures of the host-guest materials and thus led to different drug release properities.