化学
苯并恶唑
噻唑
催化作用
苯甲酸
脱羧
组合化学
有机化学
药物化学
作者
Kai Xie,Zhiyong Yang,Xingjian Zhou,Xiujian Li,Sizhuo Wang,Ze Tan,Xiangyu An,Can‐Cheng Guo
出处
期刊:Organic Letters
[American Chemical Society]
日期:2010-03-04
卷期号:12 (7): 1564-1567
被引量:191
摘要
A Pd-catalyzed decarboxylative coupling of thiazoles and benzoxazole with various substituted benzoic acids is developed. The reaction is compatible with both electron-rich and electron-poor benzoic acids. It can also be extended to the synthesis of polyfluoro-substituted biaryls using polyfluorobenzenes as the starting materials.
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