A One-Pot Approach for the Preparation of Novel Anil-Like Compounds from 2,3-Dihydroxynaphthalene

Background: A series of novel anil-like compounds was constructed via a three-component domino condensation of 2,3-dihydroxynaphthalene, triethylorthoformate and heteroaryl amines in the presence of formic acid catalyst under solvent-free conditions. Significant features of this method are: simplicity of the procedure, clean reaction, short reaction time, the ready accessibility, and cost effectiveness of the catalyst, high yields, easy work-up and purification of novel products by non-chromatographic methods. Keywords: Anil, 2, 3-Dihydroxynaphthalene, Heteroarylamine, Triethylorthoformate, Schiff-base.