Metabolite profiles of formula milk compared to breast milk.

食品科学 母乳 哺乳期 羊奶 婴儿配方奶粉
作者
Paola Scano,Antonio Murgia,Martina Demuru,Roberto Consonni,Pierluigi Caboni
出处
期刊:Food Research International [Elsevier BV]
卷期号:87: 76-82 被引量:25
标识
DOI:10.1016/j.foodres.2016.06.024
摘要

Breast milk (BM) feeding is the gold standard in neonate nutrition. When BM is not available it can be substituted or integrated with commercial formula milk (FM) usually sold under different brands and formulations. In this work, the low-molecular-weight hydrophilic compounds in milk were studied by gas chromatography electronic impact mass spectrometry (GC-MS), comparing eight different FM brands with BM samples. With the aid of multivariate statistical data analysis, a marked variability among FM brands, especially driven by the presence of prebiotics in their formulation, was highlighted. Quali-quantitative differences were found between FM and BM. Orotic acid and isomaltulose were found exclusively in FM, while phenylalanine and tyrosine levels were high in two FM brands. Moreover, higher levels of malic acid, sugars (glucose, fructose and galactose), and mannitol were detected in FM. On the other hand, BM showed a higher amino acid content. In conclusion, GC-MS proved to be a very sensitive analytical technique for the study of FM, highlighting metabolite differences among FM brands, and between FM and BM, that may have a possible strong impact on neonatal nutrition.
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