纳米孔测序
纳米孔
生物
基因组学
计算生物学
基因组
纳米技术
遗传学
基因
材料科学
作者
Ying Xu,Hongbing Luo,Zhili Wang,Hon-Ming Lam,Cheng Huang
标识
DOI:10.1016/j.tplants.2021.11.004
摘要
Oxford Nanopore Technology (ONT) is one of the most promising long-read technologies able to produce ultra-long reads, which can overcome issues encountered with short reads, such as characterizing structural variants and highly repeated regions. ONT documents various bases and modifications of native DNA and RNA by detecting the changes in ionic current signals corresponding to the characteristics of each nucleotide passing through a nanopore. ONT enables researchers to explore plant genomes, transcriptomes, and epigenomes at an unprecedented resolution.
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