分子印迹聚合物
印记(心理学)
分子印迹
纳米技术
基因组印记
聚合物
化学
材料科学
选择性
生物化学
基因
有机化学
基因表达
催化作用
DNA甲基化
作者
Xiaopeng Fu,Yan Li,Shuang Gao,Yongqin Lv
标识
DOI:10.1002/jssc.202100137
摘要
Abstract Molecularly imprinted polymers, developed 50 years ago, have garnered enormous attention as receptor‐like materials. Lately, molecularly imprinted polymers have been employed as a specific target tool in favor of cancer diagnosis and therapy by the selective recognition of tumor cells. Although the molecular imprinting technology has been well‐innovated recently, the cell still remains the most challenging target for imprinting. In this review, we summarize the advances in the synthesis of molecularly imprinted polymers suitable for the selective recognition of tumor cells. Through a sustained effort, three strategies have been developed including peptide‐imprinting, polysaccharide‐imprinting, and whole‐cell imprinting, which have resulted in inspiring applications in effective cancer diagnosis and therapy. The major challenges and perspectives on the further directions related to the synthesis of molecularly imprinted polymers were also outlined.
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