Does the type of seizure influence heart rate variability changes?

心率变异性 癫痫 医学 心脏病学 内科学 发作类型 麻醉 心率 血压 精神科
作者
Teresa Faria,Susana Rodrigues,Manuel Campelo,Duarte Dias,Ricardo Rego,Helena Rocha,Francisca Sá,Marta Tavares-Silva,Roberto Pinto,Gonçalo Pestana,Ana Oliveira,Jorge Pereira,João Paulo Silva Cunha,Francisco Rocha-Gonçalves,Hernâni Gonçalves,Elisabete Martins
出处
期刊:Epilepsy & Behavior [Elsevier BV]
卷期号:126: 108453-108453 被引量:4
标识
DOI:10.1016/j.yebeh.2021.108453
摘要

Heart rate variability (HRV), an index of the autonomic cardiac activity, is decreased in patients with epilepsy, and a low HRV is associated with a higher risk of sudden death. Generalized tonic-clonic seizures are one of the most consistent risk factors for SUDEP, but the influence (and relative risk) of each type of seizure on cardiac function is still unknown. Our objective was to assess the impact of the type of seizure (focal to bilateral tonic-clonic seizure - FBTCS - versus non-FBTCS) on periictal HRV, in a group of patients with refractory epilepsy and both types of seizures.We performed a 48-hour Holter recording on 121 patients consecutively admitted to our Epilepsy Monitoring Unit. We only included patients with both FBTCS and non-FBTCS on the Holter recording and selected the first seizure of each type to analyze. To evaluate HRV parameters (AVNN, SDNN, RMSSD, pNN20, LF, HF, and LF/HF), we chose 5-min epochs pre- and postictally.We included 14 patients, with a median age of 36 (min-max, 16-55) years and 64% were female. Thirty-six percent had cardiovascular risk factors, but no previously known cardiac disease. In the preictal period, there were no statistically significant differences in HRV parameters, between FBTCS and non-FBTCS. In the postictal period, AVNN, RMSSD, pNN20, LF, and HF were significantly lower, and LF/HF and HR were significantly higher in FBTCS. From preictal to postictal periods, FBTCS elicited a statistically significant rise in HR and LF/HF, and a statistically significant fall in AVNN, RMSSD, pNN20, and HF. Non-FBTCS only caused statistically significant changes in HR (decrease) and AVNN (increase).This work emphasizes the greater effect of FBTCS in autonomic cardiac function in patients with refractory epilepsy, compared to other types of seizures, with a significant reduction in vagal tonus, which may be associated with an increased risk of SUDEP.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
刚刚
刚刚
123发布了新的文献求助10
2秒前
暖暖完成签到,获得积分10
3秒前
4秒前
18621058639完成签到,获得积分10
4秒前
pbj发布了新的文献求助10
5秒前
额我认为发布了新的文献求助10
5秒前
M27发布了新的文献求助10
5秒前
在水一方应助vvvaee采纳,获得10
6秒前
djf点儿完成签到 ,获得积分10
7秒前
8秒前
Hhl完成签到,获得积分10
9秒前
9秒前
爆米花应助好运采纳,获得10
10秒前
Lucas应助pbj采纳,获得10
10秒前
redchocobo发布了新的文献求助10
10秒前
通辽小判官完成签到,获得积分10
11秒前
newgeno2003发布了新的文献求助10
11秒前
11秒前
大个应助科研通管家采纳,获得10
11秒前
隐形曼青应助科研通管家采纳,获得10
12秒前
怡然的芯发布了新的文献求助10
12秒前
赘婿应助科研通管家采纳,获得10
12秒前
科研通AI2S应助科研通管家采纳,获得10
12秒前
12秒前
12秒前
7275XXX完成签到,获得积分10
12秒前
sujustin333发布了新的文献求助10
13秒前
清梦完成签到,获得积分10
13秒前
15秒前
NexusExplorer应助沟通亿心采纳,获得10
15秒前
顾矜应助123321采纳,获得10
15秒前
细心觅风完成签到,获得积分10
17秒前
铅笔995发布了新的文献求助20
17秒前
大个应助ryd采纳,获得10
17秒前
18秒前
Yi羿完成签到 ,获得积分10
19秒前
19秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance 500
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3970008
求助须知:如何正确求助?哪些是违规求助? 3514711
关于积分的说明 11175563
捐赠科研通 3250077
什么是DOI,文献DOI怎么找? 1795198
邀请新用户注册赠送积分活动 875630
科研通“疑难数据库(出版商)”最低求助积分说明 804931