乳腺癌
微生物群
生物标志物
肠道菌群
免疫系统
医学
癌症
治疗方法
肿瘤科
免疫学
生物信息学
内科学
生物
疾病
生物化学
作者
Sabine Dieleman,Romy Aarnoutse,Janine Ziemons,Loes Kooreman,Annemarie Boleij,Marjolein L. Smidt
标识
DOI:10.1016/j.ajpath.2021.02.020
摘要
Breast microbiota holds many possibilities to reveal more insight into the pathophysiology of breast cancer. Using the breast microbiome as a marker to predict breast cancer prognosis and therapeutic response holds promise. Targeting microbiota could be used to improve therapeutic efficiency and reduce related toxicity. Before breast microbiota analysis can be implemented, major knowledge gaps need to be considered. There is limited understanding of the contribution of breast microbiota to cancer development and treatment response. Because indications exist that breast microbiota components interact with the gut microbiota and the immune system, these need to be explored in parallel.
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