Effect of Cisplatin and Gemcitabine With or Without Berzosertib in Patients With Advanced Urothelial Carcinoma
吉西他滨
医学
顺铂
肿瘤科
内科学
转移性尿路上皮癌
癌症
泌尿科
化疗
膀胱癌
尿路上皮癌
作者
Sumanta K. Pal,Paul Frankel,Amir Mortazavi,Matthew I. Milowsky,Ulka N. Vaishampayan,Mamta Parikh,Yung Lyou,Peng Weng,Rahul Atul Parikh,Benjamin A. Teply,Robert Dreicer,Hamid Emamekhoo,M. Dror Michaelson,Christopher Hoimes,Tian Zhang,Sandy Srinivas,William Y. Kim,Yujie Cui,Edward M. Newman,Primo N. Lara
出处
期刊：JAMA Oncology [American Medical Association] 日期：2021-08-26卷期号：7 (10): 1536-1536被引量：34
Preclinical studies suggest that inhibition of single-stranded DNA repair by ataxia telangiectasia and Rad3 (ATR) may enhance the cytotoxicity of cisplatin, gemcitabine, and other chemotherapeutic agents. Cisplatin with gemcitabine remains the standard up-front therapy for treatment in patients with metastatic urothelial cancer.
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science
VDC
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坚强的广山
聪明灵阳
36456657
毛豆
tuanheqi
渊崖曙春
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