肌萎缩侧索硬化
间充质干细胞
医学
细胞外小泡
骨髓
干细胞
疾病
病理
细胞生物学
生物
出处
期刊:International Journal of Science and Research Archive
[GSC Online Press]
日期:2021-06-30
卷期号:2 (2): 167-171
被引量:5
标识
DOI:10.30574/ijsra.2021.2.2.0058
摘要
Amyotrophic Lateral Sclerosis (ALS) is a terminal neurodegenerative disease with only a few minimally effective treatment options. This study treats a patient with Spinal ALS with Bone Marrow Derived Mesenchymal Stem Cell Extracellular Vesicles (BM-MSCEVs) to slow or stop the progress of the disease. After 2 months and 4 treatments, the patient demonstrated improvement in ALS functional scores and most physical exam findings. BM-MSCEVs demonstrate the ability to effectively treat Spinal ALS in this study and open the door for future studies.
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