脆弱类杆菌
生物
微生物学
致癌物
上皮
毒素
细胞
癌变
癌症研究
遗传学
基因
抗生素
作者
Liam Chung,Erik Thiele Orberg,Abby L. Geis,June L. Chan,Kai Fu,Christina E. DeStefano Shields,Christine M. Dejea,Payam Fathi,Jie Chen,Benjamin B. Finard,Ada Tam,Florencia McAllister,Hongni Fan,Xinqun Wu,Sudipto Ganguly,Andriana Lebid,Paul Metz,Sara W. Van Meerbeke,David L. Huso,Elizabeth C. Wick
标识
DOI:10.1016/j.chom.2018.02.004
摘要
(Cell Host & Microbe 23, 203–214; February 14, 2018) As a result of a production oversight in the originally published version of this article, three author names were printed incorrectly. Erik Thiele Orberg’s name was incorrectly tagged; Thiele Orberg’s first name is Erik, and his surname is Thiele Orberg. Christina E. DeStefano Shields' name was incorrectly tagged; DeStefano Shields is the complete and correct surname. Lastly, Florencia McAllister's name was printed with an erroneous middle initial. These errors have now been corrected online. The journal apologizes for the errors and any inconvenience that may have resulted. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial CellsChung et al.Cell Host & MicrobeFebruary 1, 2018In BriefChung et al. uncover a complex, microbe-driven carcinogenic mechanism whereby the Bacteroides fragilis toxin targets the colonic epithelium to trigger an IL-17 mucosal immune response that relays back to epithelial cells, inciting pro-tumoral myeloid cell infiltration, principally to the distal colon, corresponding to the region of tumorigenesis in ApcMin/− mice. Full-Text PDF Open Archive
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