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Sci‐Sat AM(2): Brachy‐01: A novel HDR Ir‐192 brachytherapy water calorimeter standard

近距离放射治疗 材料科学 克尔玛 吸收剂量 剂量学 量热计(粒子物理) 核医学 光学 物理 探测器 放射治疗 医学 内科学
作者
Arman Sarfehnia,Jan Seuntjens
出处
期刊:Medical Physics [Wiley]
卷期号:35 (7Part3): 3416-3416
标识
DOI:10.1118/1.2965993
摘要

Parameters influencing the accuracy of absorbed dose measurements for HDR 192Ir brachytherapy using water calorimetry were investigated with the goal to develop a novel primary absorbed dose to water standard. To provide greater stability, flexibility, and accuracy in the source-detector distance dsrc-det positioning and measurement, a new spring-loaded catheter holder composed of two concentric cylindrical sleeves with multiple orthogonal adjusting screws was developed. The absorbed dose from Nucletron microSelectron-HDR 192Ir brachytherapy sources with air kerma strengths ranging between 21000-38000 U was studied. dsrc-det is optimized so as to balance signal-to-noise ratio (decreasing with increasing dsrc-det ) and temperature drift effects resulting from source self-heating. The irradiation times were adjusted to yield a minimum 1 Gy of dose at the measurement point. Successful measurements at dsrc-det ranging between 25-50 mm were performed. COMSOL MULTIPHYSICS™ software was used to determine the heat loss correction due to conduction defined as the ratio between temperature rise at a point under ideal conditions to realistic conditions (i.e., no conduction). An agreement of better than 6.5% was observed between TG-43 calculated and calorimetrically measured absorbed dose rates. The effects of convection where calculated to be negligible as the glass vessel provides a convective barrier significantly decoupling the water velocity in the interior and exterior of the vessel (water velocities were 1-2 orders of magnitude different). Our work paves the way to successful primary absorbed dose determination for radioactive sources using calorimetric techniques.

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