[Beta-adrenergic receptors in the cardiovascular system. The participation of propranolol insensitive beta-adrenoceptors in the regulation of the cardiovascular system].

In this paper we described the participation of beta-adrenoceptors in the regulation of the cardiovascular system. We characterized mainly the low-affinty state of beta1-adrenoceptors and beta3-adrenoceptors, which are insensitive to propranolol (the antagonist of beta1-/beta2-adrenoceptors). We also illustrated their function in the healthy and failing heart. In addition the vasodilatory effects of these receptors ligands were described.