前列腺癌
医学
药学
癌症
前列腺
药物输送
癌症治疗
药理学
内科学
纳米技术
材料科学
作者
Wanxiao Sun,Yaxin Deng,Meihui Zhao,Ying Jiang,Jingxin Gou,Yanjiao Wang,Tian Yin,Yu Zhang,Haibing He,Xing Tang
标识
DOI:10.1016/j.jconrel.2021.01.010
摘要
For the past few years, nanotechnology has provided a lot of new treatment opportunities for prostate cancer patients, and brilliant achievements have been acquired indeed. It not only prolonged circulation time in vivo but also increased bio-availability of drugs. Among them, nanoparticles with specificity ligand can be better targeted at prostate cancer, which improves the curative effect and reduces side effects. What's more, in terms of combined administration, the synergistic effect of chemotherapeutic drugs and hormones, or co-delivery two or more different drugs into the same delivery system, has achieved good therapeutic progress as well. In this paper, a comprehensive overview of nano-technology and the combination therapy for prostate cancer by pharmaceutical and clinical pharmaceutical strategies have been proposed to further appreciate and recommend the design and development of prostate cancer treatment.
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