医学
肢端皮损性黑色素瘤
布雷斯洛厚度
黑色素瘤
皮肤病科
流行病学
结节性黑色素瘤
回顾性队列研究
人口
置信区间
浅表扩散性黑色素瘤
疾病
作者
Pei Ming Yeo,Ziying Vanessa Lim,Wei Ding Virlynn Tan,Xiahong Zhao,Hui Yi Chia,Suat Hoon Tan,Melissa Ching Ching Teo,Melissa Wee Ping Tan
出处
期刊:Annals Academy of Medicine Singapore
[Academy of Medicine, Singapore]
日期:2021-06-01
卷期号:50 (6): 456-466
被引量:1
标识
DOI:10.47102/annals-acadmedsg.2020535
摘要
Introduction: Melanomas in Asians have different clinicopathological characteristics and prognosis from melanomas in Caucasians. This study reviewed the epidemiology and treatment outcomes of cutaneous melanoma diagnosed at a tertiary referral dermatology centre in Singapore, which has a multiracial population. The study also determined whether Asians had comparable relapse-free and overall survival periods to Caucasians in Singapore. Method: This is a retrospective review of cutaneous melanoma cases in our centre between 1996 and 2015. Results: Sixty-two cases of melanoma were diagnosed in 61 patients: 72.6% occurred in Chinese, 19.4% in Caucasians and 3.2% in Indians, with an over-representation of Caucasians. Superficial spreading melanoma, acral lentiginous melanoma and nodular melanoma comprised 37.1%, 35.5% and 22.6% of the cases, respectively. The median time interval to diagnosis was longer in Asians than Caucasians; median Breslow’s thickness in Asians were significantly thicker than in Caucasians (2.6mm versus 0.9mm, P=0.018) and Asians tend to present at a later stage. The mortality rates for Asians and Caucasians were 52% and 0%, respectively. Conclusion: More physician and patient education on skin cancer awareness is needed in our Asian-predominant population for better outcomes. Keywords: Asian, melanoma, nails, skin neoplasm, survival
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