混合器
微观混合
混合(物理)
材料科学
纳米颗粒
壳聚糖
制作
微流控
纳米技术
化学工程
物理
医学
替代医学
病理
量子力学
工程类
作者
Kefan Guo,Yao Chen,Zheng Zhou,Shu Zhu,Ni Zhang,Nan Xiang
出处
期刊:Electrophoresis
[Wiley]
日期:2022-08-03
卷期号:43 (21-22): 2184-2194
被引量:8
标识
DOI:10.1002/elps.202200077
摘要
Current three-dimensional micromixers for continuous flow reactions and nanoparticle synthesis are complex in structure and difficult to fabricate. This paper investigates the design, fabrication, and characterization of a novel micromixer that uses a simple spatial Tesla valve design to achieve efficient mixing of multiple solutions. The flow characteristics and mixing efficiencies of our Tesla valve micromixer are investigated using a combination of numerical simulations and experiments. The results show that in a wide range of flow rates, viscoelastic solutions with different concentrations can be well mixed in our micromixer. Finally, experiments on the synthesis of chitosan nanoparticles are conducted to verify the practicability of our micromixer. Compared with nanoparticles prepared by conventional magnetic stirring, the size of nanoparticles prepared by micromixing is smaller and the distribution is more uniform. Therefore, our Tesla valve micromixer has significant advantages and implications for mixing chemical and biological reactions.
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