Riboflavin Metabolism

THE importance of riboflavin (vitamin B2) in human nutrition has long been appreciated, despite the absence of an easily detectable deficiency syndrome. As the precursor of two coenzymes that participate in a wide variety of reactions in intermediary metabolism, riboflavin exerts an important controlling influence on bodily processes. In recent years quantitative methods have become available for assessing riboflavin nutrition and for exploring the pathophysiology of the deficiency state. Boles for the vitamin have been found in carcinogenesis, in teratogenesis and in hematologic disorders. New information has been obtained on hormonal regulation of riboflavin utilization. The present review . . .