动脉自旋标记
血流
心脏病学
核磁共振
缺血
磁共振血管造影
作者
Matthias J.P. van Osch,Wouter M. Teeuwisse,Zhensen Chen,Yuriko Suzuki,Michael Helle,Sophie Schmid
标识
DOI:10.1177/0271678x17713434
摘要
With the publication in 2015 of the consensus statement by the perfusion study group of the International Society for Magnetic Resonance in Medicine (ISMRM) and the EU-COST action ‘ASL in dementia’ on the implementation of arterial spin labelling MRI (ASL) in a clinical setting, the development of ASL can be considered to have become mature and ready for clinical prime-time. In this review article new developments and remaining issues will be discussed, especially focusing on quantification of ASL as well as on new technological developments of ASL for perfusion imaging and flow territory mapping. Uncertainty of the achieved labelling efficiency in pseudo-continuous ASL (pCASL) as well as the presence of arterial transit time artefacts, can be considered the main remaining challenges for the use of quantitative cerebral blood flow (CBF) values. New developments in ASL centre around time-efficient acquisition of dynamic ASL-images by means of time-encoded pCASL and diversification of information content, f...
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