Synthesis and Application of Uronic Acids

This review concerns selected methods for the synthesis of uronic acids and uronic acid-containing oligosaccharides. Construction of uronic acids is broadly represented by methods based on carbohydrates and non-carbohydrates as well as de novo synthesis. Oxidation of carbohydrates is presented for both monosaccharides and oligosaccharides by using various methods including TEMPObased protocols. Keywords: Carbohydrates, monosaccharides, oxidation, stereoselective synthesis, uronic acids.