静电纺丝
伤口敷料
生物相容性
伤口愈合
成纤维细胞
壳聚糖
纳米纤维
MTT法
材料科学
生物医学工程
乳酸
淀粉
化学
体外
复合材料
外科
食品科学
医学
聚合物
生物化学
冶金
生物
细菌
遗传学
作者
Eda Yeniay,Leyla Öcal,Esra Altun,Betül Giray,Faik N. Oktar,Ahmet Talat İnan,Nazmi Ekren,Osman Kılıç,Oguzhan Gunduz
标识
DOI:10.1080/00914037.2018.1525718
摘要
Wound dressings are very useful materials for accelerating the wound healing process. In this study, nanofibrous wound dressings were produced from blending solution of Poly-lactic acid(PLA)/Chitosan(C)/Starch(S)/Zinc oxide(Z) by electrospinning method. Morphology, chemical interaction, mechanical, water uptake and weight loss tests were performed on each samples. Moreover, the biocompatibility of primary dermal fibroblast (ATCC, PCS-201-012) on prepared wound dressings was investigated with MTT assays in vitro, and the samples were found suitable for cell viability and proliferation. These results suggest that produced nanofibrous wound dressings can be promising candidate for wound dressing applications.
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