重氮
环加成
环戊烯
烯烃
环丙烷化
亲核细胞
化学
电泳剂
光催化
光化学
有机化学
药物化学
催化作用
作者
Francisco Sarabia,Qiankun Li,Eric M. Ferreira
标识
DOI:10.1002/anie.201805732
摘要
A direct (3+2) cycloaddition between alkenes and vinyl diazo reagents using either Cr or Ru photocatalysis is described. The intermediacy of a radical cation species enables a nucleophilic interception by vinyl diazo compounds, a departure from their traditional electrophilic behavior. A variety of cyclopentenes are synthesized using this method, and experimental insights implicate a direct cycloaddition instead of a cyclopropanation/rearrangement process.
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