哮喘
肺
巨噬细胞
免疫学
炎症
医学
癌症研究
细胞生物学
生物
内科学
体外
生物化学
作者
Seunghan Han,Bomin Kim,Do Young Hyeon,Daeun Jeong,Jae-Chan Ryu,Jae Sung Nam,Yoon Ha Choi,Boram Kim,Sang Chul Park,Youn Wook Chung,Sung Jae Shin,June‐Yong Lee,Jong Kim,Jihye Park,Sei Won Lee,Tae‐Bum Kim,Jae Hee Cheon,Hyung‐Ju Cho,Chang‐Hoon Kim,Joo‐Heon Yoon,Daehee Hwang,Ji-Hwan Ryu
标识
DOI：10.1038/s41467-024-53038-2
摘要
The IL-23-Th17 axis is responsible for neutrophilic inflammation in various inflammatory diseases. Here, we discover a potential pathway to inhibit neutrophilic asthma. In our neutrophil-dominant asthma (NDA) model, single-cell RNA-seq analysis identifies a subpopulation of CD39
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