医学
怀孕
血管阻力
肺动脉高压
危险分层
队列
心力衰竭
疾病
心脏病学
重症监护医学
内科学
产科
血流动力学
遗传学
生物
作者
Jenny Y. Mei,Richard N. Channick,Yalda Afshar
标识
DOI:10.1016/j.hfc.2022.08.019
摘要
Pulmonary hypertension is one of the highest risk medical conditions in pregnancy and carries significant maternal morbidity and mortality as well as neonatal morbidity. Diagnosis is commonly delayed due to the nonspecific nature of early symptoms. Disease progression can lead to right ventricular failure, which carries mortality rates as high as 25% to 56%. Pregnancy-related complications arise from cardiac inability to accommodate increased plasma volume and cardiac output, decreased systemic vascular resistance, and hypercoagulability. Patients in this high-risk cohort necessitate preconception risk stratification and multidisciplinary care throughout their pregnancy and delivery planning.
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