药物输送
冲程(发动机)
医学
药品
缺血性中风
癌症治疗
神经科学
靶向给药
细胞疗法
药理学
干细胞
癌症
纳米技术
生物
缺血
内科学
细胞生物学
材料科学
机械工程
工程类
作者
Hao Cui,Sha Ma,Ye Yang,Chengxiao Wang
出处
期刊:Pharmaceutics
[MDPI AG]
日期:2023-12-19
卷期号:16 (1): 6-6
被引量:5
标识
DOI:10.3390/pharmaceutics16010006
摘要
Ischemic stroke (IS) is a prevalent form of stroke and a leading cause of mortality and disability. Recently, cell membrane-derived nanovehicles (CMNVs) derived from erythrocytes, thrombocytes, neutrophils, macrophages, neural stem cells, and cancer cells have shown great promise as drug delivery systems for IS treatment. By precisely controlling drug release rates and targeting specific sites in the brain, CMNVs enable the reduction in drug dosage and minimization of side effects, thus significantly enhancing therapeutic strategies and approaches for IS. While there are some reviews regarding the applications of CMNVs in the treatment of IS, there has been limited attention given to important aspects such as carrier construction, structural design, and functional modification. Therefore, this review aims to address these key issues in CMNVs preparation, structural composition, modification, and other relevant aspects, with a specific focus on targeted therapy for IS. Finally, the challenges and prospects in this field are discussed.
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