New Iridoids and Acyclic Monoterpenoids from the Roots and Rhizomes of Valeriana officinalis var. latifolia

Abstract Five new iridoids, valeralides A–E ( 1 – 5 ), two new acyclic monoterpenoids, valeralides F ( 6 ) and G ( 7 ), together with two known iridoids ( 8 and 9 ), were isolated from the roots and rhizomes of Valeriana officinalis var. latifolia . Their structures were elucidated based on 1D and 2D NMR, as well as HR‐ESI‐MS spectroscopic data. The absolute configuration of compounds 1 – 4 were elucidated based on electronic circular dichroism (ECD) calculation. In addition, all the isolates were evaluated for their inhibition on nitric oxide production, cytotoxicity and anti‐influenza A virus activity.