化学
硒化物
芳基
加合物
电解
电化学
组合化学
立体选择性
药物化学
离子液体
有机合成
有机化学
催化作用
硒
烷基
电极
物理化学
电解质
作者
Li Sun,Mengcan Xia,Guorui Yu,Sheng Liu,Yafei Wu,Kun Zhao,Biming Mao
标识
DOI:10.1002/adsc.202301289
摘要
Abstract This research presents a method for the oxidative selenylation and thiolylation of Morita‐Baylis‐Hillman adducts through constant‐current electrolysis in an undivided cell at room temperature. The reaction enables direct production of trisubstituted ( Z )‐allyl aryl selenides and sulfides with yields of 27–98%. A wide variety of different functionalities are well tolerated under these reaction conditions. This strategy could be carried out on gram scale and several synthetic transformations were accomplished for the construction of other allyl selenide derivatives. Control experiments and mechanistic studies indicate a radical or an ionic addition pathway for this electrochemical transformation.
科研通智能强力驱动
Strongly Powered by AbleSci AI