The Characteristics of Concurrent Anti-Glomerular Basement Membrane Nephritis and Membranous Nephropathy

Concurrent anti-glomerular basement membrane (GBM) nephritis and membranous nephropathy (MN) is rare and previously addressed only in case reports or small series (≤12 patients)1-3. The target antigen(s) in MN associated with anti-GBM nephritis are unknown. We report the clinicopathologic characteristics and outcome of 28 patients with this dual glomerulopathy, which were among 449 (6.2%) anti-GBM nephritis and 5183 (0.5%) non-lupus MN cases diagnosed at a large nephropathology laboratory over a 23-year period (Supplementary methods).