Diiodine–Triethylsilane System: Formation of N-Alkylsulfonamides from Benzylic Alcohols and Sulfonamides

Abstract An operationally simple method has been developed for the synthesis of N-alkylsulfonamides from benzylic alcohols and sulfonamides in the presence of molecular iodine and triethylsilane. Various benzylic alcohols and sulfonamides were evaluated, and iodides generated in situ were shown to be the key intermediates.