伤口愈合
植皮术
医学
人体皮肤
免疫系统
移植
皮肤修复
皮肤病科
外科
皮肤移植
免疫学
生物
遗传学
作者
Bryan K. Sun,Zurab Siprashvili,Paul A. Khavari
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2014-11-20
卷期号:346 (6212): 941-945
被引量:720
标识
DOI:10.1126/science.1253836
摘要
The ability of the skin to repair itself after injury is vital to human survival and is disrupted in a spectrum of disorders. The process of cutaneous wound healing is complex, requiring a coordinated response by immune cells, hematopoietic cells, and resident cells of the skin. We review the classic paradigms of wound healing and evaluate how recent discoveries have enriched our understanding of this process. We evaluate current and experimental approaches to treating cutaneous wounds, with an emphasis on cell-based therapies and skin transplantation.
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