A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides

Simple and efficient: The combination of an enzymatic, enantioinverting reaction with simple follow-up processes allows the transformation of readily available racemic compounds into versatile chiral α-substituted amides (see picture; Ms=methanesulfonyl). These important building blocks are prepared in high overall yield and enantiomeric excess; the elimination of intermediate purification steps results in a time- and cost-efficient process. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.