Application of the TIMI Risk Score for ST-Elevation MI in the National Registry of Myocardial Infarction 3

FFECTIVE RISK STRATIFICATION IS integral to management of acute coronary syndromes. 13][4] Early risk assessment guides triage to alternative levels of hospital care, decisions regarding therapeutic interventions, and application of clinical pathways that direct patient care and use of clinical resources.Despite wellcharacterized risk predictors, 5-7 reliable quantitative estimation of risk is challenging, as patients present with complex risk profiles requiring integration of numerous elements of qualitative and quantitative data.Thus, practical tools that enhance clinicians' ability to rapidly and accurately assess risk are of substantial interest.The Thrombolysis in Myocardial Infarction (TIMI) risk score for STEMI is a simple integer score that can be used at the bedside for risk stratification of patients at presentation with STelevation acute coronary syndromes. 8Derived from 14114 patients enrolled in the InTIME II (Intravenous nPA for Treatment of Infarcting Myocardium Early) trial, the TIMI risk score is a ro-