囊性纤维化
医学
肺移植
囊性纤维化跨膜传导调节器
移植
肺
肺病
气道
疾病
重症监护医学
内科学
胃肠病学
外科
作者
Malcolm Brodlie,Ali Aseeri,Jim Lordan,Andrew Robertson,Michael C McKean,Paul A. Corris,S M Griffin,N. J. Manning,Jeffrey P. Pearson,Chris Ward
出处
期刊:The European respiratory journal
[European Respiratory Society]
日期:2015-10-22
卷期号:46 (6): 1820-1823
被引量:35
标识
DOI:10.1183/13993003.00891-2015
摘要
Cystic fibrosis (CF) is a genetic condition that is caused by abnormalities in the CF transmembrane conductance regulator ( CFTR ) gene. People with CF experience life-long morbidity and premature mortality, the vast majority of which is associated with lung disease. Bile acids are detectable in the lower airway in advanced CF lung disease and persist after lung transplantation We gratefully acknowledge the help of the patients involved in this study along with all members of the wider cardiothoracic transplantation team at the Freeman Hospital.
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