Comprehensive geriatric assessment for older adults admitted to hospital: meta-analysis of randomised controlled trials

医学 置信区间 优势比 奇纳 梅德林 老年病科 荟萃分析 随机对照试验 子群分析 家庭医学 物理疗法 急诊医学 心理干预 内科学 护理部 精神科 政治学 法学
作者
Graham Ellis,Martin A Whitehead,David J. Robinson,Desmond O’Neill,Peter Langhorne
出处
期刊:BMJ [BMJ]
卷期号:343 (oct27 1): d6553-d6553 被引量:985
标识
DOI:10.1136/bmj.d6553
摘要

To evaluate the effectiveness of comprehensive geriatric assessment in hospital for older adults admitted as an emergency.We searched the EPOC Register, Cochrane's Controlled Trials Register, the Database of Abstracts of Reviews of Effects (DARE), Medline, Embase, CINAHL, AARP Ageline, and handsearched high yield journals.Randomised controlled trials of comprehensive geriatric assessment (whether by mobile teams or in designated wards) compared with usual care. Comprehensive geriatric assessment is a multidimensional interdisciplinary diagnostic process used to determine the medical, psychological, and functional capabilities of a frail elderly person to develop a coordinated and integrated plan for treatment and long term follow-up.Three independent reviewers assessed eligibility and trial quality and extracted published data. Two additional reviewers moderated.Twenty two trials evaluating 10,315 participants in six countries were identified. For the primary outcome "living at home," patients who underwent comprehensive geriatric assessment were more likely to be alive and in their own homes at the end of scheduled follow-up (odds ratio 1.16 (95% confidence interval 1.05 to 1.28; P = 0.003; number needed to treat 33) at a median follow-up of 12 months versus 1.25 (1.11 to 1.42; P < 0.001; number needed to treat 17) at a median follow-up of six months) compared with patients who received general medical care. In addition, patients were less likely to be living in residential care (0.78, 0.69 to 0.88; P < 0.001). Subgroup interaction suggested differences between the subgroups "wards" and "teams" in favour of wards. Patients were also less likely to die or experience deterioration (0.76, 0.64 to 0.90; P = 0.001) and were more likely to experience improved cognition (standardised mean difference 0.08, 0.01 to 0.15; P = 0.02) in the comprehensive geriatric assessment group.Comprehensive geriatric assessment increases patients' likelihood of being alive and in their own homes after an emergency admission to hospital. This seems to be especially true for trials of wards designated for comprehensive geriatric assessment and is associated with a potential cost reduction compared with general medical care.
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